Autism spectrum disorder (ASD) represents a big and diverse group of childhood developmental disorders of unknown etiology. It is identified by deviations in social communication and interaction, and atypicality in characteristics of common behaviour and interest. Some children show exceptional abilities, that is, talents for certain areas (music, memory, art, mathematics etc.). Disorders manifest themselves before the age of three, and the occurances are more common in male children. According to DSM-IV classification, spectrum of disorders includes: autism disorder, Rett syndrome, disintegrative disorder, Asperger's syndrome and Pervasive Developmental Disorder, Not Otherwise Specified. Aforementioned disorders are incurable, but the symptoms can be alleviated, in some cases even removed, with adequate therapeutical and educational procedures, thus enabling an ASD child to use certain skills. In the past, children with autism spectrum disorder were considered to be incapable of being educated and therefore sent to special departments of institutions for children with intellectual disabilities. Today, children with ASD can be integrated in regular classes through different forms. Because they are facing difficulties, they need to be provided with corresponding professional help. The teacher should acquire thorough knowledge regarding autism, work together with parents and other experts who are participating in student's education and recognize individual needs of every student with ASD and act accordingly. For teaching to be successful, the teacher must create an individualized educational programme, use appropriate strategies of assistance in and outside the classroom and learn to deal with problematic student behaviour.