The aim of this study was three-fold: first, to determine the existence of a self-determination continuum in our socio-cultural conditions on an academic level, second, to determine the relationship between the academic self-regulation and the academic achievement, and third, to determine the relationship between the academic self-regulation and health. The study was performed on a sample of 217 first and second year students (159 female and 58 male) of biology and medicine. The following measurement instruments were used: Self Regulation Questionnaire-Academic (SRQ-A, Ryan and Connell, 1989), subjective evaluation of psychical and physical health and grade in test. The obtained results point to the following: In our socio-cultural conditions, on an academic level, there can be registered an existence of a self-determination continuum that the Deci-Ryan’s theory anticipates. There is a positive correlation between autonomous motivation and the grades in test. Intrinsic motivation and the college that the students attend are significant predictors for academic achievement. There is a positive correlation between autonomous motivation and health. The students with autonomous motivation had a better subjective evaluation of psychical and physical health than the students with controlled motivation. These results are discussed with reference to Deci and Ryan’s (1985, 1991) self-determination theory.